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About the application:

Stay tuned for more mini games about another microbes that threaten our health: Follow us on Twitter: @Drexel_IMMID, #IMMID, #CD4Hunter Visit our site: www.drexelmed.edu/immid Game Features: CD4 Hunter is a fast-paced, educational mini-game in which users take on the role of a human immunodeficiency virus kind 1 (HIV-1) virion. By immersing true science within easy mini game play, players learn about the first step of HIV-1’s fascinating and complex replication cycle: binding and attachment. CD4 Hunter invites users to enter the bloodstream and grow their viral population by infecting specific target cells, while evading the immune system. Download CD4 Hunter for gratis to: • Learn complex science through fast-paced and addictive mini game play • Hunt for target cells in the human bloodstream • Control and grow your viral population • Face antibody attacks as the immune system wars infection Learning Goals: CD4 Hunter is the first in a series of mini-games to be developed by the Institute for Molecular Medicine and Infectious Illness at Drexel University College of Medicine, to introduce users to the dynamic globe of infectious illness. CD4 Hunter was designed to supplement learning about the multi-stage process of the HIV-1 replication cycle, through interactive video test. This apk is intended for use in biomedical science curriculum in higher education. Players apply knowledge about the biological processes involved during HIV-1 replication to advance in the mini game. CD4 Hunter focuses on meeting the following learning objectives: 1. Identify gp120 as a primary element of HIV-1 structure and apply knowledge about its function in the process of viral binding and entry. 2. Identify CD4+ T cells as targets for HIV-1 infection in humans and apply knowledge about their role in viral pathogenesis. 3. Identify and match the molecules on the surface of HIV-1 (i.e., gp120) and T cells (i.e., CD4+ receptor, and CCR5 and CXCR4 co-receptors) involved in viral binding and entry. 4. Apply concepts of viral tropism and immune evasion mechanisms to complete the HIV-1 infection cycle in CD4+ T cells. Credits Executive Producer and Consultant Brian Wigdahl, PhD Chair, Department of Microbiology and Immunology (M&I); and Executive Director, Institute for Molecular Medicine and Infectious Illness (IMMID), Drexel University College of Medicine Subject Matter Expert and Project Supervisor   Sandra Urdaneta-Hartmann, MD, PhD, MBA Assistant Professor of M&I; and Director, the Center for Business and Tool Development at IMMID, Drexel University College of Medicine Game Designer Carla Louise Brown, PhD Postdoctoral Fellow, Department of M&I and IMMID, Drexel College of Medicine Programmer and Artist Vincent Mills Co-op student at M&I and IMMID, Mini game Art and Production Tool, Drexel University College of Media Arts and Design (Class of 2018) Animator and Artist Andrew Dean Bishop Co-op student at M&I and IMMID, Animation and Visual Effects, Drexel University College of Media Arts and Design (Class of 2018) --------------------------------------------------------------------------------- SPECIAL THANKS TO: Subject matter experts Fred Krebs, PhD; William Dampier, PhD; Michael Nonnemacher, PhD; Vanessa Pirrone, PhD; Michael Wagner, PhD; and Mary Ann Comunale. Beta testers M&I graduate students Drexel University Entrepreneurial Mini game Studio *** Please assist us improve this mini game by reporting any bugs to [email protected]. We welcome feedback and recommendations for upgrades and improvements. *** ©2017 Drexel University