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About the application:

LUminate is the official help apk designed to help patients taking LUCEMYRA (lofexidine) tablets as they go through opioid withdrawal. With customizable dose tracking, timely medication reminders, and everyday mes- sages of encouragement, the LUminate apk is designed to help patients while they go through withdrawal during each day of treatment with LUCEMYRA. Signup is not needed — simply download the apk and begin immediately! FEATURES INCLUDE: - Dose Tracking/Reminders - Supportive messages each day of treatment - Symptom Library (including tip and advices for relief) - Meditation Timer INDICATION LUCEMYRA is indicated for mitigation of opioid with- drawal symptoms to facilitate abrupt opioid discontinu- ation in adults. IMPORTANT SAFETY INFORMATION LUCEMYRA will not stop you from craving opioids. LUCEMYRA is not an opioid and will not produce the effects seen when taking opioids. LUCEMYRA may lessen the severity of your symptoms, but it may not completely prevent them. After a period of not using opioids, you may be more sensitive to the effects of lower amounts of opioids. Taking opioids in amounts that you used before stop- ping opioid use, whether with or without LUCEMYRA, can lead to overdose and death. It is necessary that you, your family, and the people closest to you are aware of this increased risk of overdose. Alcohol, barbiturates, and benzodiazepines could be used with caution while taking LUCEMYRA as serious side effects may occur. Tell your healthcare provider if you have ever been diag- nosed with kidney illness or liver disease. LUCEMYRA may cause low blood pressure or slower heart rate. Tell your healthcare provider if you have ever been diagnosed with low blood pressure, slow heart rate, any another cardiac abnormality (including prior di- agnosis or family history of long QT syndrome), or if you have had a heart attack. Tell your healthcare provider about all medications you are taking. LUCEMYRA could be used with caution with any medications that decrease pulse or blood pressure. Watch for signs of a drop in your blood pressure or heart rate, including dizziness, lightheadedness, or feelings of faintness either when sitting or if you quickly stand up. If you experience these symptoms, call your healthcare provider and do not take your next dose of LUCEMYRA until you have talked to your healthcare provider. It is necessary to stay hydrated while taking LUCEMYRA during opioid discontinuation or withdrawal. The most common side effects seen with LUCEMYRA are low blood pressure or symptoms such as lighthead- edness, slow heart rate, dizziness, sleepiness, and dry mouth. Talk to your healthcare provider before taking another medications for individual symptoms of withdrawal (such as pain relievers, sleep aids, or medications for upset stomach). Your healthcare provider will tell you whether it is secure to take LUCEMYRA with another medi- cations you may be prescribed during opioid discontin- uation (such as buprenorphine/naloxone, methadone, naltrexone). LUCEMYRA could not be stopped abruptly. Consult your healthcare provider before stopping or reducing your LUCEMYRA dose. To report SUSPECTED ADVERSE REACTIONS or product complaints, contact US WorldMeds at 1-833-LUCEMYRA or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. The LUminate Help Apk is for your private use only. By using the LUminate Help Apk, you under- stand and acknowledge the info that you place into the LUminate Help Apk will not be accessed by anyone another than you. Please note that all comments posted on iTunes are not associated with, endorsed by, or monitored by US WorldMeds, LLC. US WorldMeds will not answer to comments posted on iTunes. Instead, please contact us directly at 1-833- LUCEMYRA. If you are experiencing a medical emergency, call 911 immediately.