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While population growth can bring economic benefits, it can also place a strain on resources and infrastructure, leading to health and social challenges. This rapid growth compromises the availability and quality of primary services including, health, education, and social safety, and contributes to the rapid depletion of natural resources. This is in addition to the globally looming threats of water scarcity, meal crisis, and climate change, which all jeopardize the sustainability and economic development of countries around the globe. Additionally, the globe is facing an aging demographic. The global population aged 60 years and above is expected to reach two billion by 2050, increasing the need for specialized services including healthcare, social safety, and rehabilitation. Since population dynamics contribute to the complexity of bringing health to all, health systems must answer actively to changes taking put in the growth, structure, and distribution of the world's population. This requires leveraging the role of basic healthcare as well as adopting innovative measures to face this challenge. The global burden of illness is also shifting, with a growing burden of non-communicable diseases such as cardiovascular illness, cancer, as well as mental health disorders, which are becoming a major global health problem, with depression and anxiety affecting millions of people worldwide. There is also a need to improve sexual and reproductive health, with a lot of countries still struggling to provide adequate access to contraception and maternal healthcare.